MECHANISM OF ACTION
1-DNA Dependent RNA Polymerase- Rifampcin
2- RNA Dependent DNA Polymerase- Zidovudine
3-Proetin Synthesis Blocker- Erythromycin, Chloramphenicol & Tetracycline
4-ACE Inhibitor- Captopril
5-Ca Channel Blocker- Nifedipine, Diltiazem
6-COX Inhibitor- Asprin
7-GABA Facilitator- Benzodiazepines
8-Antimetabolites- Methotrexate
9-Loop Diuretics- Frusemide
10-High Ceiling Diuretics- Spironolactone
11-Alteration of bacterial DNA- Choloroquine
12-Inhibition of Viral replication- Amantidine, Acyclovir
13-H1 blocking agent- Mepyramine, Loratadine
14-H2 Blocking agent- Rantidine, Cimetidine, Famotidine, Cyprohaptidine
15-Proton Pump inhibitor- Omeprazole
16-DNA Metabolism Inhibitors- Quinacrine (Mepacrine)
17-Spindle Poison- Vinca, Griesofulvin
18-Folic acid synthesis inhibitor- DDS
19-GABA Inhibitor- Sodium Valproate
20-DNA Synthesis Prevention – Nalidixic Acid
21-Prostaglandin Synthesis Inhibition- Oxyphenbutazone, Ibuprofen
22-Mycolic acid synthesis inhibition- INH
23-Folic acid antagonist- MTX, PAS, DDS & Primethamine
24-Desruption of DNA structure- MNZ
25-Inhibition of cell wall synthesis- Beta lactam antibiotics (penicillin)
26-Release of nor epinephrine- Ephedrine
27-Ergosterol Biosnythesis Inhibitors- Clotrimazole, Miconalzole, Ketoconazol
28-Ach esterase inhibitors- Physostigmine, Neostigmine, Edrophonium, Metrifonate
29-Reverse Transcriptase Inhibitors- Stavudine, zidovudine
30-Inhibition of HIV Protease- Amepranavir
31-DNA Gyrase Inhibitor- Cinoxacin
32-Inhibition of DNA Polymerase-Gossypol
33-NMDA Receptor Antagonist- Amantadine, Ketamine, Dextromethorphan, Memantine &
Nitrous Oxide
34-DNA intercalating agent- Daunorubicin, Doxorubicin, Ellipticin & Ethidium Bromide
35-Antim mitotic agent- Amphethenile
36-Alkylating agent- Thiotepa
37-Alpha receptor antagonist- Phentolamine
38-Beta receptor antagonist- Propanolol, Aplrenolol
39-Alpha receptor agonist- Norepinehrine
40- Beta receptor agonist- Isoproterenol & Salbutamol
41-DNA Adduct Formation- Procarbazine
42-Carbonic anhydrase inhibitor- Acetazolamide
43-Phosphodiestrase Inhibitor- Theophylline
44-Thrombin action prevention- Heparin
45-Xanthine oxidase inhibitor- Allopurinol
46-Cholinergic Blockade- Ipratropium
47-Adenosine Deaminase inhibitor- Crisnatapase
48-Immunomodulation- Imiquimod
49-Amino acid transfer interference- Econazole
50-Mast Cell Stabilization- Ketosifen